A similar pattern as for the ipsilateral striatum was also found in the contralateral striatum although the effect did not reach statistical significance (p = 0.053, Fig. 3 b).
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Diet-induced weight loss in obese/diabetic mice normalizes glucose metabolism and promotes functional recovery after stroke.
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0.0530
0.1000
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a strong trendp ≈ 0.1
However, CD68 expression showed a strong trend toward an increase in ipsilateral striatum of T2D/Ob mice vs. non-T2D mice (p ≈ 0.1, Fig. 3 d, f) and this trend was abolished by weight loss in T2D/WL mice (p ≈ 0.1, Fig. 3 d, f).