The Synbiotic Combination of <i>Akkermansia muciniphila</i> and Quercetin Ameliorates Early Obesity and NAFLD through Gut Microbiota Reshaping and Bile Acid Metabolism Modulation.

Antioxidants (Basel) · 2021 · PMC8698339 · PMID 34943104

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showed a trendno p-value reported

Contrarily, Srebp1c expression, a regulator of fatty acid synthesis, showed a trend to increase when the diet was supplemented with the synbiotic.

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did not reach statistical significanceno p-value reported

Regarding BA synthesis, the synbiotic approach upregulated Cyp7a1 and Cyp8b1 expression, yet the increase in Cyp7a1 did not reach statistical significance ( Figure 7 A).

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