Protracted Impairment of Maternal Metabolic Health in Mouse Dams Following Pregnancy Exposure to a Mixture of Low Dose Endocrine-Disrupting Chemicals, a Pilot Study.

Toxics · 2021 · PMC8706199 · PMID 34941779

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0900

boldest claim

The sentences

failed to reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

MIX dams had a mean adipose volume of 673 mm 3 in MIX dams compared to 511 mm 3 in vehicle dams, though this failed to reach statistical significance (t = −1.57, p = 0.07, Cohen’s d = 0.83; data not shown).

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did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Furthermore, MIX dams had an average visceral adipose volume to body volume ratio of 0.09 while the vehicle dams had an average ratio of 0.07; however, this did not reach statistical significance (t = −1.49, p = 0.08, Cohen’s d = 0.79, Figure 3 C). 3.4.

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marginally significantp = 0.09so close (0.05 < p ≤ 0.1)

Over the course of the glucose tolerance test, blood glucose concentrations exhibited a marginally significant interaction between time and treatment (F(20,72) = 1.5, p = 0.09), with MIX dams showing a significantly elevated glucose area under the curve compared to vehicle dams ( p = 0.033, Cohen’s d = 1.63, Figure 1 C).

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