Preliminary Exploration of the Sequence of Nerve Fiber Bundles Involvement for Idiopathic Normal Pressure Hydrocephalus: A Correlation Analysis Using Diffusion Tensor Imaging.

Spearman correlation analysis also revealed a moderately significant correlation between the FA value in the splenium of the CC and the INPHGS urination score ( r = 0.424, p = 0.027) and an almost significant correlation between the FA value in the head of the CN and motor function (the INPHGS gait score) ( r = −0.379, p = 0.051) ( Figure 2 ).

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There was a negative, nearly significant correlation between the ADC in the head of the CN ( r = −0.357, p = 0.068) and in anterior limb of IC ( r = −0.326, p = 0.097) and the MMSE score and a strong, negative and significant correlation between the ADC in the posterior limb of the IC and the MMSE score ( r = −0.468, p = 0.014).

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