Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy.

J Neuroinflammation · 2021 · PMC8719395 · PMID 34972522

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp=0.08so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

Similarly, PS19 mice treated with etanercept showed a trend (p=0.08) towards an increase in brain IĸBα compared to saline-treated PS19 mice, but this data did not reach statistical significance.

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