Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models.

A strong trend towards higher urinary albumin/creatinine ratio in EMPA treated mice compared with H 2 0 control animals was detected, but the observed differences did not reach statistical significance ( Figure 6B ).

also in 5,725 other papers

There was a slight trend toward increased water intake and urine volume in the EMPA group, without reaching statistical significance ( Figure 4D ).

also in 4,078 other papers

The slight trend toward reduced hyperfiltration in EMPA treated animals did not reach statistical significance and did not persist until week 4.

also in 111,027 other papers