Lung cancer patients had significantly increased fibrinogen levels and INR (B fbg = 1.84, P < .001, B INR = 0.244, P = .01), as well as aPTT, but with borderline significance (B APTT = 2.24, P = .05); PT% values were significantly lower (B PT = −14.27, P = .003).
54 In our study throughout the course of time fibrinogen levels remained higher in patients with progressive disease, whereas TF-Ag levels varied, albeit those differences did not reach statistical significance.
Overall MPTF and TF-Ag showed a trend of inverse relationship, whereas TF-Ag and ANG-2 maintained trend of positive relationship over time ( Supplemental Table S7 ).