Acute Hypophagia and Changes in c-Fos Immunoreactivity in Adolescent Rats Treated with Low Doses of Oxytocin and Naltrexone.

J Clin Med · 2021 · PMC8745073 · PMID 35011797

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0680

boldest claim

The sentences

approached significancep = 0.057so close (0.05 < p ≤ 0.1)

It should be noted that the OT−0.3 mg/kg NTX combination only approached significance ( p = 0.057) though variability in response to the treatment was higher (coefficient of variation of 49.2) here than in other groups (OT + 0.1 mg/kg NTX: 46.5; OT + 1 mg/kg NTX: 41.8).

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approaching significancep = 0.068so close (0.05 < p ≤ 0.1)

In addition, all three treatments caused a decrease in Fos in the BLA (F(3, 32) = 13.36; p < 0.001 for each; NTX: d = 1.64; OT: d = 2.35; OT + NTX: d = 2.03), and an increase in the CeA (though in the case of OT, it was approaching significance at p = 0.068, whereas for NTX p = 0.009, d = 0.92, and OT + NTX p = 0.001, d = 2.95; F(3,32) = 7.86).

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