Health Care Costs of Target Attainment for Beta-Lactam Antibiotics in Critically Ill Patients: A Retrospective Analysis of the EXPAT Study.

Ther Drug Monit · 2022 · PMC8746885 · PMID 33770020

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.1260

boldest claim

The sentences

a strong trendP = 0.063so close (0.05 < p ≤ 0.1)

Costs associated with the transfusion of blood products were significantly higher in patients with target attainment (€90.60 and €12.70, P = 0.023), with a strong trend toward higher RRT costs in this patient category (0 and 0, P = 0.063).

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showed a trendP = 0.103not close (p > 0.1)

Target attainment showed a trend toward higher total ICU costs (€44,600 versus €28,200, P = 0.103).

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trend toward significanceP = 0.126not close (p > 0.1)

The trend toward significance ( P = 0.126) of target attainment in the univariate analysis did not translate in the multivariate analysis.

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