In control-treated mice, we detected a reduced number of observed bacterial species, although this difference did not reach statistical significance ( Figure 3 c).
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NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease.
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Notably, alcohol-fed Nlrp6 -deficient mice showed a trend towards reduced Muc2 expression compared to alcohol-fed WT mice ( Figure 2 c), consistent with a slightly reduced mucus layer in the colon ( Figure 2 b).