Lipid-Associated Variants near ANGPTL3 and LPL Show Parent-of-Origin Specific Effects on Blood Lipid Levels and Obesity.

However, the maternally inherited G allele was significantly associated with lower ApoB/ApoA1 ratio: the differences in the effect of the paternal and maternal G on ApoA1 and APoB/ApoA1 ratio were nominally significant, whereas the POE on ApoA2 was significant after correction for multiple testing.

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When looking at obesity related traits, the G allele showed a trend to lower waist-hip ratio with and without adjusting for BMI when inherited maternally and increased ratio when inherited paternally in both Botnia and HTB.

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