DP thymocytes were significantly elevated in WT B6.Nba2 mice and the numbers were partly reversed in B6.Nba2 cKO mice, although the changes did not reach statistical significance ( p = 0.06) ( Figure 5 B).
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Spontaneous CD4+ T Cell Activation and Differentiation in Lupus-Prone B6.Nba2 Mice Is IFNAR-Independent.
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Further analysis of CD8+ T cell subsets, showed a trend towards increased levels of CD44 high CD62L low CD8+ T cells in B6.Nba2 versus B6 mice, which was partly reversed in B6.Nba2 cKO mice ( Figure 1 E).