Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells.

A clear trend towards lower cap‐dependent translation was detected for RPL10‐R98S ribosomes (Figure 2F ).

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In line with this Ba/F3 cell data, Jurkat RPL10‐R98S mutants showed a trend towards a 20% decrease for all three proteasomal activities (Figure 2D ).

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