Dapagliflozin Ameliorates the Formation and Progression of Experimental Abdominal Aortic Aneurysms by Reducing Aortic Inflammation in Mice.

Oxid Med Cell Longev · 2022 · PMC8816542 · PMID 35126822

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showed a trendno p-value reported

Dapagliflozin treatments significantly attenuated medial SMC loss and showed a trend for the preservation of elastin as compared to vehicle treatment.

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failed to reach statistical significanceno p-value reported

However, the difference failed to reach statistical significance between 1 mg/kg dapagliflozin and vehicle treatment, although a reduced trend was noted ( p = 0.07).

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