Sitagliptin Is More Effective Than Gliclazide in Preventing  Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease.

Notably, gliclazide-treated mice appeared to have some inhibition of ERK phosphorylation ( Figure 8 A), although this did not reach statistical significance ( Figure 8 C).

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Sitagliptin significantly improved the hyperinsulinemia and showed a trend to improve insulin resistance ( Figure 1 C,D).

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