a statistical trendp = 0.070
Comparably, plasma citH3 was significantly elevated in AAA patients versus healthy controls ( p = 0.046) and showed a statistical trend to be elevated in AAA compared to the PAD group ( p = 0.070).
Comparably, plasma citH3 was significantly elevated in AAA patients versus healthy controls ( p = 0.046) and showed a statistical trend to be elevated in AAA compared to the PAD group ( p = 0.070).
In contrast to oxLDL, a weak inhibitory effect of HDL and natLDL on NET release was observed, which did not reach statistical significance.
In this setup, native LDL and HDL showed a trend to decrease DNA release by primed neutrophils (mean 18.5 RFU, natLDL: 13.8 RFU, HDL: 13.4 RFU), while oxLDL significantly enhanced the A23187-primed NET formation (25.7 RFU).