DSS treatment showed a trend of decline in expression of ZO-1 , Occludin , and Claudin-2 ( Figure 4 C–E).
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Novel Role of Ghrelin Receptor in Gut Dysbiosis and Experimental Colitis in Aging.
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In the young group, the weight of the spleen was significantly increased in DSS-treated KO compared to control KO; the weight of the spleen of DSS-treated KO had a trend of increase compared to WT, but it did not reach statistical significance ( Figure 3 D).