Bovine Natural Antibody Relationships to Specific Antibodies and <i>Fasciola hepatica</i> Burdens after Experimental Infection and Vaccination with Glutathione <i>S</i>-Transferase.

However, the naïve IgM NAb levels may reflect the subsequent SpAb production post-vaccination, as there is a strong trend in the associations between KLH-binding IgM NAbs to both anti-GST SpAb IgG ( Figure 5 A: r = 0.80, p = 0.06) and IgM ( Figure 5 B: r = 0.72, p = 0.11).

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However, the control group did show a negative trend between final fluke burdens and the anti-KLH IgM responses post-challenge (Day 84: r = −0.76, p = 0.08), with the group showing no trends to fluke weights. 3.6.

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