1 b, respectively, median (IQR) sCOMP and sHA values were higher in the LOA group compared to the EAO and healthy group, but these differences did not reach statistical significance ( p > 0.05).
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Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study.
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Serum HA levels showed a trend of slight increase as OA severity increased, but these differences did not reach statistical significance ( p > 0.05) (Fig. 1 b).