Midwall Fibrosis and Cardiac Mechanics: Rigid Body Rotation Is a Novel Marker of Disease Severity in Pediatric Primary Dilated Cardiomyopathy.

Although we could see a clear trend toward more pronounced LV dysfunction and higher NT-proBNP levels in MWF+ patients, a larger patient cohort may be needed to demonstrate statistically significant differences between MWF– and MWF+ patients with regard to clinical and functional markers of heart failure.

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In our study, we could see a trend toward a more pronounced LV systolic dysfunction and reduction of GLS, GCS and GRS as well as higher NT-proBNP levels in MWF+ patients, but our results did not reach statistical significance.

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