A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.

However, survival benefits experienced by this arm did not reach statistical significance (Fig EV3I ).

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Indeed, in a reduced number of eight matched samples including primaries that relapsed later on and their corresponding metastases (Table EV8 ) we observed that mean H score showed a trend to be higher in metastases than in the primary tumor (Table EV8 ).

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