Results: SRp55 rs2235611 genotype distribution and allele frequency were similar in SSc and healthy controls, though a trend toward significance was observed for genotype distribution (p=0.07).
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A mild trend to have a higher rate of hypovitaminosis D (81,3% vs 68,3%), arthralgia (47% vs 32%), GERD (66% vs 52%), ILD (36% vs 27%), anti CCp positive (12% vs 7%), electrocardiogram abnormalities (19% vs 10%) and PAH (50% vs 32%) was observed in pts-SSc with nRAD compared to those without.
Difference between patient and control groups is highly significant (p <0.001).
Subjects with PRP showed a trend towards a worse performance than HC, without reaching statistical significance due to low number of patients. 2) An application containing three games based on the gestures tested in this study and adapted to facilitate the use by SSc patients was developed.
There were also differences in the other parameters included in risk stratification assessments, although these did not reach statistical significance.