The expression level of Mmp12 in AMD macular tissues appeared to be higher than that in non-AMD controls but the difference did not reach statistical significance ( p = 0.194 by Welch’s t test, Fig. 8 A).
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Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis.
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0.1940
0.1940
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2 A) and qRT-PCR showed a trend, but statistically insignificant reduction ( p = 0.058, Fig. 2 B).