Neutralization of GDF15 Prevents Anorexia and Weight Loss in the Monocrotaline-Induced Cardiac Cachexia Rat Model.

Cells · 2022 · PMC8997866 · PMID 35406637

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showed a trendno p-value reported

GDF15 mAb2 treatment showed a trend in attenuating the reduction in tibialis anterior and gastrocnemius muscle mass in rats dosed with MCT but this effect did not reach statistical significance.

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did not reach statistical significanceno p-value reported

Reductions in gastrocnemius and tibialis anterior muscle mass induced by MCT were attenuated by mAb2 treatment but did not reach statistical significance ( Figure 2 E,F).

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