Subgroup analysis of RCTs revealed a trend toward lower mortality in the BC group but did not reach statistical significance compared with NS (RR 0.92, 95% CI 0.82–1.02, p = 0.11, I 2 = 41%, Figure 2 B).
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Balanced Crystalloids versus Normal Saline in Adults with Sepsis: A Comprehensive Systematic Review and Meta-Analysis.
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Subgroup analysis of RCTs showed a trend toward lower incidence of AKI in the BC group but did not reach statistical significance compared with NS (RR 0.71, 95% CI 0.47–1.06, p = 0.09, I 2 = 0%, Figure 4 B). 3.3.3.