Decreased total CXCR5 + CD4 + T cells and increased CCR7 + , PD1 + , PD1 hi , ICOS + and ICOS + PD1 + cTfh-cell sub-populations were evidenced in ePTC as compared to sPTC but did not reach statistical significance (Fig. 6a, b ).
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Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers.
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First, ePTC showed a trend towards a decrease of total B cells, which was inversely correlated with the frequency of viremic episodes in the range of 50–400 copies/ml (Fig. 5a ).