Contrary to rosiglitazone alone and in combination with losartan, no weight gain was observed in the group taking rosiglitazone in combination with metformin, but this difference failed to reach statistical significance, indicating that metformin did not sufficiently ameliorate weight gain under rosiglitazone [ 133 ].
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PPAR-Targeted Therapies in the Treatment of Non-Alcoholic Fatty Liver Disease in Diabetic Patients.
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Furthermore, liver stiffness measurement (LSM) by vibration-controlled transient elastography (VCTE) and controlled attenuation parameter (CAP) decreased, but this did not reach statistical significance [ 78 ].