Barely Significant
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DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome.

Front Genet · 2022 · PMC9094685 · PMID 35571061

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closest p · 1.0× alpha
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The sentences

nominally significantp -value<0.05actually significant
For 18S_1 , 18S_2 , and 28S targets, we found few CpG sites showing nominally significant association ( p -value<0.05) of DNAm with age.

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showed a trendno p-value reported
The EpiTYPER analysis showed a trend toward rDNA hypermethylation in DS compared to CTRL that reached statistical significance (q-value <0.05) for some CpG units, thus confirming the results generated by targeted-bisulfite sequencing ( Supplementary Figure S4 ).

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