Aerobic exercise elicits clinical adaptations in myotonic dystrophy type 1 patients independently of pathophysiological changes.

J Clin Invest · 2022 · PMC9106360 · PMID 35316212

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.1200

boldest claim

The sentences

failed to reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

Similarly, MFN-2, p-DRP1 Ser637 , and t-DRP1 increased following exercise, but increases failed to reach statistical significance ( P = 0.06, P = 0.08, and P = 0.06, respectively; Figure 8, A–C ).

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did not reach statistical significanceP = 0.12not close (p > 0.1)

Absolute and relative FEV1 values were increased by approximately 5% and approximately 7%, respectively, in response to training, but did not reach statistical significance (unadjusted P = 0.12 and 0.067, respectively).

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