Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis.

EBioMedicine · 2022 · PMC9118662 · PMID 35576644

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Gene expression data from previous studies corroborated the exclusive longitudinal association of B cell activation in responders (FDR=0.017, Supplementary Table 17), and showed a trend for cell killing activation in non-responders, although it did not reach statistical significance (FDR=0.072, Supplementary Table 18).

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