Production of New Microbially Conjugated Bile Acids by Human Gut Microbiota.

Biomolecules · 2022 · PMC9139144 · PMID 35625615

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a clear trendno p-value reported

The in vitro results showed a clear trend to first accumulate the epimer isoursochenodeoxycholic acid and the dehydroxylated lithocholic acid derivatives in samples incubated with chenodeoxycholic and 3-oxo-chenodeoxycholic acid.

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a strong trendno p-value reported

They also showed a strong trend for the production of microbially conjugated dehydroxylated bile acids instead of chenodeoxycholic backbone conjugates.

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