Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis.

Mol Pharm · 2022 · PMC9175178 · PMID 35271294

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

36 When comparing the effect of GE11 modification, we observed an increasing trend that did not reach statistical significance for the accumulation of GE11-modified polymeric micelles compared to the plain ones in orthotopic HCT116 tumors 24 h postinjection, irrespective of the micellar core structure ( Figure 8 ).

also in 111,027 other papers

showed a trendno p-value reported

The GE11-modified micelles showed a trend in enhancing the accumulation of micellar carrier in primary orthotopic HCT116 tumors and a significant reduction of tumor growth when loaded with A83B4C63, in vivo compared to untreated controls.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.