DNA Methylation Analysis of Turner Syndrome BAV.

Although no TFBS reached significance, we found that known regulators of heart valve development PBX3 and PKNOX1 were 15 and 19-fold enriched, respectively, which approached significance ( q values = 0.1041) ( Table 2 ).

also in 8,237 other papers

Homer TFBS motif enrichment was performed and it was found that all DMRs display enrichment for PIT1 ( q value = 0.00, a regulator of hormone expression), and TBX20 approaching significance ( q value = 0.15), a known regulator of heart development ( Table 3 ) ( Pfaffle et al., 1999 ; Kirk et al., 2007 ).

also in 2,640 other papers