The effect of tocilizumab on patient reported outcomes and inflammatory biomarkers in hematopoietic cell transplantation.

Brain Behav Immun Health · 2022 · PMC9213229 · PMID 35757656

Europe PMC DOI

hedged sentences

0.0880

closest p · 1.8× alpha

0.0880

boldest claim

The sentences

approached significancep = 0.088so close (0.05 < p ≤ 0.1)

The relationship between baseline CRP and concurrent PRO scores approached significance (dCor = 0.057, p = 0.088); there were no other significant cytokine-PRO associations found. 3.4.1 Depression and inflammatory biomarkers We conducted exploratory secondary analyses focused on depression and inflammatory biomarkers.

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did not reach statistical significanceno p-value reported

Depression was higher at Day 28 compared to baseline in both groups (comparison group: +5.1 [95% CI 0.14–10, p = 0.045], tocilizumab: +8.6 [95% CI 2.3–15, p = 0.011]), though the difference between groups did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.