In our study, assessment of fibrosis by cardiac magnetic resonance showed a trend in regression of myocardial fibrosis in 18.8% of patients, without a significant difference between the groups.
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Efficacy and Safety of Granulocyte-Colony Stimulating Factor Therapy in Chagas Cardiomyopathy: A Phase II Double-Blind, Randomized, Placebo-Controlled Clinical Trial.
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In our study, there was a trend of improved VO 2 in the G-CSF group at 12 months, but it did not reach statistical significance.