Effect of Lenalidomide Maintenance in Chronic Lymphocytic Leukemia: A Meta-Analysis and Trial-Sequential Analysis.

Curr Oncol · 2022 · PMC9222174 · PMID 35735448

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a significant trendno p-value reported

In the subgroup of PFS in high-MRD patients, which was performed on bone marrow aspirate samples using eight-color flow cytometry with a detection threshold of >0.01, a significant trend toward improved PFS was observed with lenalidomide.

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a clear trendno p-value reported

In this analysis, there was a clear trend for improved control of MRD in the lenalidomide group [ 63 ].

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