The clinical relevance of humoral immune responses to Globo H-KLH vaccine adagloxad simolenin (OBI-822)/OBI-821 and expression of Globo H in metastatic breast cancer.

Among patients with H score ≥80 for GH expression by immunohistochemistry, the vaccination group (n=42) seemed to have better PFS than the placebo group (n=23) (HR=0.59; 95% CI: 0.32 to 1.10, p=0.10), but the difference did not reach statistical significance.

also in 111,027 other papers

As shown in online supplemental figure S3 , GH expression showed a trend of correlation between primary and metastatic tumors of the same patients, but did not reach statistical significance (Pearson correlation coefficient: 0.306, p=0.0885).

also in 53,322 other papers