Interestingly, despite an increase in mitochondrial respiration and an increase in the abundance of Complex I–IV proteins, Complex V subunits were, if anything, decreased in abundance—although the magnitude of this trend did not reach statistical significance.
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The sentences
The extent of upregulation (assessed by fold-change) was greater than the reduction in the expression of downregulated proteins, and the magnitude of the overall increase in expression was significant for Complex I and IV, and approaching significance for Complex II.