Low-Density Lipoprotein Cholesterol Attributable Cardiovascular Disease Risk Is Sex Specific.

The study showed a trend toward a lower risk for aortic valve replacement in male patients with familial hypercholesterolemia (HR, 0.56; 95% CI, 0.28–1.11) compared with female patients with familial hypercholesterolemia. 37 It has been suggested that the underlying pathophysiology is different in men and women, which

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We also observed nominally significant sex‐specific differences in the risk for HF (which is likely due to the downstream effects of CAD diagnosis), which remained nominally significant in the sensitivity analyses using sex‐specific weighted scores.

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