In contrast, in Apc min/+ Msh2 fl/fl VC mice, tumors taken from ETBF-colonized mice showed a trend toward an increased mutational frequency when compared to sham tumors, although it did not reach statistical significance using a Mann-Whitney U test.
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Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene.
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