In H69 number of viable cells (vitality assay) growth in conditioned media (NHs/Dex, NHs, or Dex) showed a trend through an increase according to the MTS assay, confirming the non-toxicity of NHs or NHs/Dex (not shown).
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Therapeutic effects of dexamethasone-loaded hyaluronan nanogels in the experimental cholestasis.
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Mice treated with dex and NHs/dex showed a lower number of necrotic foci compared to DDC + Ctrl mice, but this reduction did not reach statistical significance (Fig. 6 A).