Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology.

J Neuroinflammation · 2022 · PMC9252071 · PMID 35787714

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0.0500

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a strong trendp = 0.05actually significant

Similarly, levels of pS396 showed a strong trend for a decrease ( p = 0.05) in the second cohort but remained unchanged in the first cohort (Fig. 4 D, H).

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Repopulated microglial levels of CD68, a well-known marker for reactive microglia, showed a trend toward decreasing in the subiculum of 3xTg mice (Fig. 3 H, p = 0.06) and in the subiculum and CA1 in APP/PS1 mice, although the main effect of PLX treatment was only statistically significant in APP/PS1 female mice (Additional file 6 : Fig.

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