EUS-guided radiofrequency and ethanol ablation for pancreatic neuroendocrine tumors: A systematic review and meta-analysis.

In a study, the authors recommended a minimum of 5 mm safety margin from a duct or vessel is necessary to avoid iatrogenic injuries with EUS-RFA.[ 29 ] Interestingly in our study, the amount of ethanol used for ablation showed a trend toward predicting AEs but did not reach statistical significance, likely due to small sample size and fewer studies.

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There was a trend toward a higher rate of AEs with higher ethanol amount after EUS-EA with P = 0.09 but did not reach statistical significance.

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