Co-cultures of BJ1 with the NSCLC carcinoma cell lines A549 and H520 showed a trend towards MCT4 upregulation in BJ1, however the differences were not statistically significant ( Supplementary Figures 2C, D ).
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Monocarboxylate Transporter 4 in Cancer-Associated Fibroblasts Is a Driver of Aggressiveness in Aerodigestive Tract Cancers.
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The HNSCC cell line SCC9 also significantly upregulated TOMM20 expression in the presence of BJ1, compared to its monoculture ( Figures 2K, L ), and SCC25 showed a trend towards increased TOMM20 expression in co-culture, however it did not reach statistical significance ( Supplementary Figures 2K, L ).