Kruskal-Wallis statistics indicated that the IgG responses of the non-infected/vaccinated groups showed a significant change among each other (p-value = 0.0024); however, the group-wise testing by means of the Wilcoxon rank sum test did not reach statistical significance owing to multiple comparisons that were performed.
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Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants.
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The sentences
The IgG4, but not overall IgG, IgG1, IgG2, or IgG3 distributions of patients after vaccination showed a trend towards higher p(EC 50 ) values, which were increased after three vaccinations.