Bacterial lysate add-on therapy to reduce exacerbations in severe asthma: A double-blind placebo-controlled trial.

48 placebo group) that did not reach statistical significance (IRR 0.71, 95%CI [0.39–1.26], p = 0.25) (Figure 3b ; IRR for separate 6‐month period is shown in Table S2 ).

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While proportions of CD86 + regulatory T cells of CD4 + T cells showed a trend towards a significant increase over time, regulatory T cells did not show differences over time.

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