Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney.

Br J Pharmacol · 2022 · PMC9292672 · PMID 34096053

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

ODQ pretreated efferent arterioles also showed a trend towards increased sensitivity to runcaciguat as compared with L‐NAME pretreated efferent arterioles, but the difference did not reach statistical significance (Figure 3f ).

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