Facial nerve perineural spread from cutaneous squamous cell carcinoma of the head and neck: A single institution analysis of epidemiology, treatment, survival outcomes, and prognostic factors.

Head Neck · 2022 · PMC9306800 · PMID 35224794

Europe PMC DOI

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did not reach statistical significancep = 0.158not close (p > 0.1)

showed a trendno p-value reported

Zone 2 VII disease also showed a trend toward increased recurrence risk, but this did not reach statistical significance ( p = 0.158).

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highly significantno p-value reported

2 As seen in previous studies on PNS, surgical margin status was found to be a highly significant prognostic factor for VII PNS from cSCCHN, with involved margins increasing the chances of recurrence over five times. 7 , 17 Thus, an en bloc clear margin surgical resection should ideally be aimed for to optimize patient outcomes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.