Dichloroacetate improves systemic energy balance and feeding behavior during sepsis.

JCI Insight · 2022 · PMC9309051 · PMID 35730570

Europe PMC DOI

hedged sentences

0.0559

closest p · 1.1× alpha

0.0660

boldest claim

The sentences

a decreasing trendP = 0.0559so close (0.05 < p ≤ 0.1)

Bbox1 mRNA levels showed a decreasing trend ( P = 0.0559) in septic livers ( Figure 7C ), and both circulating and hepatic deoxycarnitine levels significantly decreased in septic mice.

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a strong trendP = 0.056so close (0.05 < p ≤ 0.1)

ANCOVA analysis assessed with body mass showed that the 12 hours of average energy expenditure in the first dark cycle elicited a strong trend ( P = 0.056) of restoration by DCA during sepsis ( Figure 6I ).

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showed a trendP = 0.066so close (0.05 < p ≤ 0.1)

Plasma levels of glucose, fructose, pyruvate, and lactate were significantly lower in septic versus control mice, while circulating sucrose levels showed a trend toward lower concentrations ( P = 0.066) ( Figure 1, B–F ).

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