Diagnostic application of transcripts associated with antibody-mediated rejection in kidney transplant biopsies.

The full D + H + G model incorporating all variables demonstrated a larger ROC AUC than each of the reduced models (AUC = 70.6% in the full cohort, 69.3% in the AMRsusp group) although this did not reach statistical significance when compared with D + H in either group.

also in 111,027 other papers

We suspect this may be related to the fact AMRsusp-high cases showed a trend to being taken at a later time post-transplant, and may indicate that cut-off Banff lesion scores for diagnosis of AMR could be time-sensitive, e.g. for biopsies taken later post-transplant, the selection of a lower ptc score cut-off score for a diagnosis of AMR might increase diagnostic accuracy.

also in 53,322 other papers